If the victim has collapsed or is unconscious, call 911. Welcome to the ECHA website. The test was considered to be valid as assay acceptance criteria were fulfilled. Please upgrade your Internet Explorer to a newer version. 2 of 7 Particle size distribution (Granulometry), Solubility in organic solvents / fat solubility, Stability in organic solvents and identity of relevant degradation products, Storage stability and reactivity towards container material, Biodegradation in water and sediment: simulation tests, Additional information on environmental fate and behaviour, Short-term toxicity to aquatic invertebrates, Long-term toxicity to aquatic invertebrates, Toxicity to aquatic algae and cyanobacteria, Toxicity to aquatic plants other than algae, Endocrine disrupter testing in aquatic vertebrates – in vivo, Toxicity to soil macroorganisms except arthropods, Endocrine disrupter mammalian screening – in vivo (level 3), Direct observations: clinical cases, poisoning incidents and other, Exposure related observations in humans: other data, Additional physico-chemical properties of nanomaterials, Toxicokinetics, metabolism and distribution. The determined lowest-observed effect concentration (LOEC) and no-observed effect concentration (NOEC) were 1.9 mg/L and 1.2 mg/L, respectively The NOEC calculated for lithium ion is 0.2 mg/L. The observed effect was associated with larval/juvenile stages, but no significant effect was observed during the embryonic stage. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Chloride is the most abundant anion in humans and all animal species. Mean measured concentrations of lithium chloride ranged from 63.4 to 978 mg/L and from 99 to 109 % of nominal. EC number: 231-212-3 | CAS number: 7447-41-8. This information has not been reviewed or verified by the Agency or any other authority. A safe blood level of lithium is 0.6 and 1.2 milliequivalents per liter (mEq/L). This site is not fully supported in Internet Explorer 7 (and earlier versions). Statistically significant (p < 0.01) cumulative mortality compared to the control was observed at treatment concentration of 24.35 mg/L (21.1 mg/L no. Toxicity Information for Lithium chloride Note: Information for many chemicals is incomplete and may not be fully representative of effects on humans. Environmental parameters (water temperature, pH, LD0) were monitored during the test. Lithium toxicity can happen when this level reaches 1.5 mEq/L or higher. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner. Sublethal effects were noted in all concentrations greater than 5.4 mg/L of lithium chloride or 0.89 mg/L lithium ion (based on the 16.4% proportion of lithium's atomic weight of LiCl). Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice. Chronic toxicity symptoms following ingestion of nonlethal doses of lithium chloride with low- sodium chloride diets are thirst and polyuria. No significant differences were observed either in starting or duration of hatching. EC number: 231-212-3 | CAS number: 7447-41-8. Supporting study The chronic toxicity of lithium chloride to the early life stages of Fathead minnow, Pimephales promelas Rafinesque was investigated in a manner similar to EPA OTS 797.1000 and results were gathered in a scientific publication. All test solutions appeared clear and colourless and concentrations remained stable throughout the test. The moving average technique (Johnson 1969) was used to compute the EC50 value, based on the percent of normal larvae at study termination; the EC50 value was 6.4 mg/L (95 % confidence interval 5.68 -7.36 mg/L). This suggests that when exposed to lithium, the fathead minnow larvae were either lethally affected or not affected at all after crossing an exposure time threshold. Close Find out more on how we use cookies. Information on Registered Substances comes from registration dossiers which have been assigned a registration number. For a short time in the 1940s lithium chloride was manufactured as a salt substitute, but this was prohibited after the toxic effects of the compound were recognized. The higher your serum level, the likelier there will be both side effectsand the appearance of toxic symptoms (also ca… Close Find out more on how we use cookies. Numbers of larvae hatched daily were statistically evaluated on Day 4 and Day 5 and no significant differences were observed. Mortality of the water flea exposed for 48 hours to lithium chloride ranged from 5 % at test concentrations smaller or equal to 123 mg/L and 100 % at a concentration greater than or equal to 501 mg/L. Since mortality observed from Day 6 to Day 34 was statistically significant (p < 0.01) it is considered that the test item influenced the survival of the test organisms at larval/juvenile stage rather than at embryonic stage. (Long et al., 1998). For this purpose, eggs were exposed in a semi-static test to aqueous test media containing the test item for 34 days at a range of concentrations under defined conditions. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). Lithium hydroxide monohydrate concentration in the test solutions was determined at 5 renewal periods by flame photometry. If you have a poisoning emergency in the United States call 1-800-222-1222.