If your dose is different, do not change it unless your doctor tells you to do so. Carbonic anhydrase inhibitors are sulphonamide related drugs and may give rise to associated side effects especially with systemic treatment e.g. Superficial punctate keratitis occurred in 10 to 15% of patients and signs and symptoms of ocular allergic reaction in approximately 10%. Side effects: Most common adverse reactions are blurred vision and bitter, sour or unusual taste. Dichlorphenamide may be used to treat certain inherited muscle disorders. These medicines are not recommended during breast-feeding, because they may cause unwanted effects in nursing babies. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. The tumor‐associated carbonic anhydrase (CA, EC 4.2.1.1) isozyme CA IX is highly overexpressed in many cancer types via the hypoxia inducible factor‐1α (HIF‐1α) cascade. Your doctor may want you to increase the amount of fluids you drink while you are taking this medicine. Dorzolamide HCl Ophthalmic Solution may be used concomitantly with other topical ophthalmic drug products to lower intraocular pressure. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Hypoxic tumors expressing CA IX show a poor response to classical chemo‐ and radio‐therapy treatments. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Carbonic anhydrase inhibitors also decrease the secretion of aqueous humor (the aqueous humor is the clear fluid that fills the space between the lens and the cornea of the eyeball), which results in a decrease in intraocular pressure. The presence of other medical problems may affect the use of medicines in this class. What are Carbonic anhydrase inhibitor anticonvulsants? Side effects include paraesthesia, general malaise / fatigue, dizziness, electrolyte imbalance and depression. Be sure you have discussed this with your doctor. We comply with the HONcode standard for trustworthy health information -. Generally, the electrolyte effects of carbonic anhydrase inhibitors are mild and they are typically not used for their diuretic capacity. Acetazolamide is also used as an anticonvulsant to control certain seizures in the treatment of epilepsy. Copyright © 1993-2020 Drugs. Design and Synthesis of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs–CAIs) for the Treatment of Rheumatoid Arthritis. Effects on blood pressure or heart rate were minimal. Acetazolamide is also used as an anticonvulsant to control certain seizures in the treatment of epilepsy. The amount of medicine that you take depends on the strength of the medicine. Some side effects may occur that usually do not need medical attention. It is not intended as medical advice for individual conditions or treatment. Carbonic anhydrase inhibitors are used to treat glaucoma. Emphysema or other chronic lung disease—Use of carbonic anhydrase inhibitors may increase the risk of acidosis (shortness of breath, troubled breathing). It may be necessary for you to use another medicine or to stop breast-feeding during treatment. Call your doctor for medical advice about side effects. Following topical ocular administration, Dorzolamide HCl Ophthalmic Solution reduces elevated intraocular pressure. It is also sometimes used to prevent or lessen some effects in mountain climbers who climb to high altitudes, and to treat other conditions as determined by your doctor.