BEST Alcohol to Drink for Weight Loss. For the best drink, substitute the Coke for a Diet Coke to cut calories and sugar. Rum and coke - 97 calories. The best drink is gin martini with olives for vitamin E. Rum – between 81 to 98 calories but zero carbs and zero sugar. Margaritas and Daiquiris. The best thing I can do is to inform you on the best and worst drinks when it comes to alcohol and weight loss. Frozen Margaritas are loaded with up to 600 calories and over 70g of sugar. Alcohol Can Be Good For You? There's a … The Worst Drinks for Weight Loss. If you’re daily routine is to finish the day with a drink or two, yet you’re struggling to achieve your weight loss, there is a better way. First things first let’s talk about the benefits of drinking alcohol. Here, we go through the best alcoholic drinks to pick at the bar without sabotaging your weight-loss goals.. 1.